Table 1 Demographic data and baselines characteristics of all recruited participants (N = 23)
Characteristics | Overall | Treatment approaches | |||
|---|---|---|---|---|---|
Placebo (N=6) | Ibuprofen (N=5) | ECa250 (N=6) | ECa500 (N=6) | ||
Age (years): mean (±SD) | 26.35 (±4.99) | 24.00 (±3.85) | 24.20 (±3.20) | 29.17 (±4.62) | 27.67 (±6.53) |
Sex (%): Male | 34.78 | 16.67 | 0.00 | 50.00 | 66.67 |
Female | 65.22 | 83.33 | 100.00 | 50.00 | 33.33 |
Clinical diagnosis | |||||
Muscle pain | 4 | 1 | 1 | 1 | 1 |
Muscle and TMJ pain | 19 | 5 | 4 | 5 | 5 |
Patient-reported outcome at baseline: median (IQR) | |||||
Pain score (ranges 0–10) | 5 (1.5) | 6 (2) | 6 (1) | 5 (0.75) | 5.5 (1) |
Range of motion at baseline: mean (±SD) | |||||
Pain-free mouth opening distance (mm) | 30.22 (±10.07) | 29.00 (±7.87) | 25.80 (±11.95) | 28.17 (±9.91) | 37.17 (±9.37) |
Maximum unassisted mouth opening distance (mm) | 40.17 (±9.57) | 39.83 ± (7.20) | 36.00 (±12.53) | 41.67 (±11.55) | 42.50 (±8.09) |
Maximum assisted mouth opening distance (mm) | 44.35 (±8.36) | 44.00 ± (5.59) | 39.60 (±11.55) | 47.83 (±9.56) | 45.17 (±6.37) |
Number of tender muscles and TMJs: median (IQR) | |||||
Pain on muscle palpation (10 locations) | 3 (3) | 3.5 (2.5) | 3 (4) | 2 (0.75) | 4 (5.25) |
Pain on TMJ palpation (2 locations) | 1 (0) | 1 (0) | 1 (1) | 1 (0) | 1 (0.75) |